22 Jan

Is it Safe for Children to Take Modafinil?

Every year we find new studies and reports that reveal intriguing new applications for modafinil. Seeing as it’s widely popular among university students for its ability to help you study and learn, you might wonder if it’s okay for younger people, perhaps secondary students, to take the pill. While conclusive evidence is still scarce, there are some interesting finds that suggest modafinil could be very useful for young people.

What the makers say

The official posture as stated on Provigil’s website is that modafinil should not be taken by people under 18. This is in part due to legal issues. A pharmaceutical company by law cannot market its medicines for anyone who was not part of their clinically approved trials. In most cases, clinical trials include everyone 18 and up, however there are some exceptions. Certain products marketed towards older people for instance may not have included people in their teens or twenties. From personal experience, I was interested in getting implanted contact lenses due to my terrible myopia, but was refused at the time as the clinical testing had only been done on people 21 and older.

What this means is that the safety of modafinil on children and teens has not been thoroughly tested by the manufacturer and therefore they cannot sell it or market it to that group. But does that mean it isn’t safe?

Studies say it’s safe for children to take modafinil.

This study from back in 2005 was performed on 248 individuals ranging from 6 years of age to 17. The goal of the test was to evaluate whether modafinil could be beneficial as a treatment for ADHD. ADHD is on the rise in developed nations, with anywhere between 5 and 10% of children at risk. The current default treatment for ADHD involves amphetamine-based medicines, which have a higher potential for abuse. In the United States many teens sell their ADHD pills to other students to get a buzz or a high which some describe as similar to cocaine. In addition, amphetamine-based medicines can be addictive and difficult to quit.

When researchers looked at the effects of modafinil on the brain, they saw an opportunity to attack ADHD, and launched this investigation. The results, per the study, were excellent:

Conclusions. Modafinil film–coated tablets significantly improved ADHD symptoms at school and home as evaluated by clinicians, teachers, and parents. Treatment with once-daily modafinil was generally well tolerated, with few discontinuations as a result of adverse events.

Another major advantage found in this study was that most of the children did not experience severe side-effects. While we often talk about headaches or insomnia as troublesome issues with modafinil, researchers for children were more concerned about loss of appetite leading to anorexia. This is a common occurrence among children who take amphetamines for ADHD, and it can be a real problem as children need to maintain sufficient caloric intake to spur their physical development.

The study shows that anorexia caused by loss of appetite was considerably lower with modafinil than for amphetamines and the potential for abuse was also much lower.

So, is it safe for children to take modafinil?

The study would suggest that yes, it is. However you should talk to your doctor before administering modafinil to your child as it could have an adverse reaction with other medications he or she might be taking. Also, if you’re a teen and you’re looking to improve your academic performance with modafinil, keep in mind that simply taking a pill doesn’t magically improve your grades. You must be organized, ready to work, and in the right mindset to tackle that stack of papers or crack open the history book that’s been collecting dust on your desk.

19 Jan

How to Use Nuvigil

 How to Use Nuvigil

There are many of us in today’s society that suffer with many disorder such as narcolepsy and sleeping disorder, such as sleep apnea, that can cause extreme sleepiness and fatigue. Coffee is not strong enough to stay away, and the fact is it contains too much caffeine just like other energy drinks do, and that is not good for a humans body to intake on a daily basis. However, there is a safe drug to take that will be able to help with those obstacles and it is known as Nuvigil.

 

What Is This

  Nuvigil is a wakefulness-promoting agent that is used as an oral administration. It is also known as Armodafinil, which is the R-enantiomer of modafinil. Armodafinil is a crystalized powder that is white to off-white and it is slightly soluble in water, and also soluble in methanol. Nuvigil tablets contain the following ingredients; lactose monohydrate, croscarmellose sodium, magnesium stearate, povidone, microcrystalline cellulose, and pregelatinized starch.

 

Benefits

 

 There are many benefits of taking Nuvigil. It can help in a great way to reduce the sleepiness that occurs from other health issues, it can also be used to prevent fatigue and to help you stay away during working hours especially if you have a schedule that does not allow you to keep a normal sleeping routine, and it is also used to help certain substances in your brain, if you have an irregular sleeping pattern such as insomnia, to properly control your sleep/awake cycle. This medication is beneficial in keeping you safe at work, help in aiding the fight of fatigue, and keep your body healthy by allowing it to sleep the proper amount of time for yourself.

 

Dosage

 

 The recommended dosage for Nuvigil is about 150 mg to 250 mg taken orally as a single dose on a once a day basis, specifically in the morning time. This required amount is also given to patients who suffer from OSA or narcolepsy. The required dosage for those who suffer from Work Shift Disorder, is for them to take 150 mg once a day orally, as a single dose at about approximately 1 hour before their work shift begins. For patients with sever hepatic impairment and in geriatric patients, the dosage is requested as a smaller amount and the patient should be monitored closely.

 

Side Effects

 

 Even though Nuvigil is a recommended medication for staying awake it does, however, come with a few side effects as well. When taking this medication you may and can have headaches, nervousness, dry mouth, dizziness, nausea, and it is possible to have difficulty sleeping as well. If any of these side effects occur it is always important to tell your pharmacist or doctor. Remember that your doctor did prescribe this medication because he or she believes that the benefit of Nuvigil is greater for you than the risk of possible side effects. Normally, most individuals do not experience any type of severe side effects, however, the severe side effects that can occur are fast/pounding/irregular heartbeat, depression, hallucinations, confusion, rare thoughts of suicide, and other types of mental or mood changes and should be immediately told to your doctor right away. If anything else serious occurs such as chest pain, then it is important to get medical attention immediately.

 

Long-Term Use

 

 The effects of using Nuvigil on a long-term basis, can result in future sleeping issues. If taken for long extended periods of time, it could be hard for an individual to fall asleep on their own, and also suffer from sleeping disorders or sleeping issue in the future to come.

 

Short-Term Use

 

 It has been noted that if this medication is taken in a short amount of time, that it can cause some withdrawal symptoms. Always ask your doctor if you are ready to stop taking the medication. He or she may request you stay on it, but if you want to stop have your doctor help to slowly take you off of Nuvigil. The withdrawal symptoms will include depression, fatigue, low energy, memory problems, poor concentration, and some sleepiness. Always consult with your doctor.

 

Use As A Nootropic

 

 There are advocates that are commonly using Nuvigil in their stacks, and stack are a concoction of minerals, vitamins, and supplements that are created to give benefits that result in a positive effect, and they can work together to be more effective. Nuvigil has a higher safety margin, therefore, it is a popular stimulant in nootropic stacks. It is added to these so that whoever may use it will be less fatigued and will be allowed to perform for a longer extended amount of time.

 

Effects

 

 As an individual begins to use Nuvigil they will be able to notice the beneficial effects as well as some negative ones. It will help them to remain able to stay awake for a long time and be able to efficiently and sufficiently get through their work days or to help fight off fatigue that health issues cause. However, you could end up looking pale while on this medication, develop frequent headaches, some shortness of breathe and wheezing, irregular heart beat, fever, and possibly some frequent urination. Taking this medication causes more good to come out of it than the bad. It will help you to be able to function, with a few small bumps.

 

Research

 

 There has been a recent development discovered in the research of Nuvigil. The Center of Women’s Mental Health has done plenty of research and have examined the efficiency of taking Nuvigil in the treatment of menopause-related fatigue and every quality of life. During this study, these women received open-label armodafinil therapy for an amount of 4 weeks. These symptoms were assessed and after the open-label treatment these women were given an extension of 2 more weeks of this medication. After this duration of time, these women had improved in their symptoms of menopause.

 

History

 

 In June of 2010, a phase 2 study was revealed that armodafinil as a therapy for adults who suffered from schizophrenia, failed the effects of this drug and it was, therefore, terminated. In March of 2010 it was also denied to help with jet lag. However, it does work for sleepiness just not for these areas.

 

Final Thoughts

 

 Nuvigil has many beneficial qualities if taken. It will help in every day life, also with working throughout the day to help prevent sleepiness from occurring. Even though there are a few harmless side effects, this drugs aim is more good beneficially, than in a negative way. If taken it will definitely prove to be an incredibly wise choice to make, and doctors approve as well that it is one of the safest ways to promote awakeness.

 

13 Jan

Modafinil can Help you Exercise

If you’re looking to hold up your New Year’s resolutions then look no further than modafinil. But what does the leading drug for alertness and wakefulness have to do with exercise? The benefits of modafinil for your workouts may surprise you.

Exercise Longer with Modafinil

One of modafinil’s main effects is the ability to enhance concentration and focus for whatever activity you might be doing during your dose. How does this apply to exercise? Proper exercise requires attention to form in order to perform specific movements more efficiently and to avoid injury. If your exercise plan includes weight-lifting, then you’ll find modafinil will help sustain your attention and improve your focus when performing your reps.

If you’re keener on endurance exercises, such as bicycling or running, modafinil can help your distances in the same way. The increased focus on the exercise itself will help to distract you from the exhaustion and pain associated with the activity. You’re effectively blocking it out with modafinil.

Exercise Harder with Modafinil

Related to the previous point, modafinil has the ability to reduce pain mildly. Sharper pains on modafinil are more likely to be mild, dull aches. This can be helpful with workouts, but it comes with some risk. If you exercise on modafinil, remember that pain is your body’s natural communication system. It’s your body’s way of saying that what you’re doing is pushing your limits. While modafinil may reduce this sensation, it doesn’t mean that you’re free to go. You could push yourself too far and risk injury with the pain-reducing effect of modafinil.

Another risk is dehydration. Since modafinil is a diuretic, you’ll find yourself passing water faster on the pill. With workouts your body expends a significant amount of water in sweat, so it’s important to stay extra hydrated while working out on modafinil.

Form Better Exercise Habits with Modafinil

The most important thing that modafinil does for everyone is helping you to commit to an activity. Whether it’s studying, working, or a personal activity like working out, modafinil will help you construct better habits. As it’s an all-day pill you’re more likely to have an organized, productive day. Now imagine that effect over the course of a week. You can use modafinil to establish solid habits, like working out three days a week. Replace your morning coffee with a modafinil pill and plan your week, then watch it unfold beautifully. And you’ll save money too.

The proof is in the rules: Modafinil is banned from most every sports league, and several players have been suspended from play for using modafinil. In some cases, Olympic gold-winning athletes have had their medals stripped away for using modafinil. Major sports legislators from FIFA to the NFL have banned the substance due to the fact that it helps athletes perform better, longer, and harder. But if you’re not a professional athlete, and you’re in a country where modafinil is legal to import, consider giving it a try to help improve your exercise habits and performance.

Make those New Year’s resolutions stick with modafinil at your side.

12 Jan

Keep your New Year’s Resolutions with Modafinil

If you’re anything like me and most other people out there, every year you try to set at least one goal for yourself. New Year’s resolutions have the tendency to fall apart in short order. Anyone who’s gotten a gym membership in January knows how full the car park gets, and how empty it is in February (if you’ve hung around long enough).

So with that in mind, I wanted to take a look at how modafinil could help people with their New Year’s resolutions.

New Year’s Resolution: Lose Weight / Get into Shape

By far the number one option, whether it’s losing 10lb or toning those muscles. So how can you keep this resolution with modafinil? Well for one, modafinil is being tested for clinical approval for weight loss. Modafinil reduces appetite, the ultimate enemy of the weight loss goal. A pill day can keep cravings away and help you stick to a more rigid diet.

Another benefit is that modafinil can improve your exercise routines by giving you some additional focus and stamina. It’s a banned substance in almost every sports league for this very fact. I’ve taken it before going on runs and find that I can stay concentrated on my form and I’ve seen a small improvement in distance as well. Having said that, it’s important to hydrate more than usual if you’re taking modafinil while working out. As modafinil dehydrates you faster, you’ll need to replenish plenty of fluids to avoid cramps and have a safe workout.

New Year’s Resolution: Complete a Project

This one is a little vague, because it covers so many things. Maybe it’s that website you’ve always wanted to start, or the business venture in the back of your head. Perhaps you need to add a wing onto the house, or you’ve got a novel you’re dying to write. Whatever your project is, you can use modafinil to give you the extra focus needed to get the job done right, and in the timeframe you desire.

Speaking from my personal experience as a writer, modafinil helps to streamline my mind and put together clearer thoughts and more organized material. It’s great for writing articles, quite a few of the ones you’ve read here were written on modafinil.

Nevertheless, it’s important to be organized first. Modafinil won’t magically make plans for you, but it will help you follow those plans and maximize your daily potential. Several business owners and writers have commented on how modafinil helped them to be more productive. It might just be the spark you need.

New Year’s Resolution: Learn to (insert activity here)

If you’re already in university, then this should be on your list of resolutions anyway. But if you’re no longer a student, you might have an interest in learning a new language, picking up a sport, or finally figuring out how to play the keytar. Whatever you’d like to learn, modafinil can help you out. As discussed on this site before, modafinil can improve your memory and aid in the acquisition of new information. Learning can sometimes be boring as well, and that’s where the extra concentration and attentiveness will benefit you. I was taking modafinil with some Italian classes in 2015, and found that I was more engaged in the lesson and participated more than I normally would.

Those are a few of the most common resolutions that modafinil might work for. If you’ve got any other New Year’s resolutions that you want to make good on, let us know and share your modafinil experiences.

03 Jan

How Long does Modafinil Last?

It’s widely known that modafinil is commonly taken to sustain energy throughout the day. It was designed to prevent people from falling asleep, so it has to work for a while. Yet how long does modafinil actually last and stay in your body? And what does that have to do with the effects of the pill itself?

Half-lives Matter

A number that’s often thrown around when this question comes up is the “half-life” of the medicine. The term “half-life” refers to the time it takes for there to be half of a given amount of a substance. The term originates with nuclear physics, where an unstable element decays into another one at a fixed rate and thus makes it easy to calculate its half-life. For instance, if you had 100kg of cesium-137, a common nuclear waste isotope, you’d have only 50kg after 30 years. That’s one half-life, and if you wait another, you’d get 25kg in 60 years, and so on.

In the body however the process gets trickier, because we’re not talking about a stable, constant, observable nuclear process. The human body has many more variables that make it hard to pin down the exact process. One way that medical researchers determine the half-life of a medicine is to measure its concentration in the patient’s blood. Seeing as it’s the blood that carries medicine to the places it’s needed, it makes sense that we should measure its content there.

Modafinil reaches peak blood plasma concentrations quickly: In about 2-3 hours after taking the pill you will be at maximum modafinil capacity. So how long will it stay there? To understand this we have to talk about how modafinil is composed of two enantiomers, or mirror versions of the same substance. Even though they are nearly identical forms of the same compound, they can have different effects on the body. In modafinil’s case the pill you take is a 50/50 mixture of the R and S enantiomers, and their half lives are different: 15 hours for the R and 4 for the S.

So, just take 15 and 4, get 19, divide by two and we’ve got our average half-life, right? Well it’s still not quite that simple because the R enantiomer is the one that’s responsible for most of the function of modafinil. This is so true that they’ve recently started selling only the R enantiomer on its own as “armodafinil”. So in reality modafinil’s half-life is closer to 10-12 hours, probably less than twelve.

Why does the half-life matter so much? Effectively it tells us when the medicine should be wearing off. By the half-life time, it’s literally half as potent as it was before, which can mean that it no longer affects certain systems in your body. And in medicine a half-life is not necessarily linear, it can come very suddenly. It serves as a useful market to note where and when your medicine is going to stop working and it helps doctors plan dosage schedules.

Just to speak from personal experience, I find that around 10 hours after I take modafinil it’s less powerful. In fact, it’s usually right around that time that I start feeling a little tired. By 12 hours, I feel like I could sleep pretty soon, though not quite yet. For me it’s about 15 hours before I can sleep, and at that point in time less than 50mg of my original 200mg is still in my body. Most users report similar findings.

How long do large doses of modafinil last?

If you take bigger doses the same rules apply. For instance, if you took 400mg of modafinil you’ll be down to about half of that in roughly 10 hours, meaning that you still have 200mg in your system and you should be able to continue working on that dose. That dose will take another 10 hours to reduce to 100mg. So a large 400mg dose could keep you active for an entire 24-hour day. As with everything in the human body it gets more complicated: You build up short-term tolerance to virtually every drug, reducing its potency as you go. This is different from the long-term tolerance which prevents you from feeling the same effects day after day over the course of a long time. Short-term tolerance is very short-term, perhaps within the same hour or so. Eventually you may notice that your extra dose isn’t having an equal effect, and this is normal. Plus, as you’ve been working hard the whole day, that extra modafinil is making up for a lot of exhaustion, and there’s only so much it can do.

400mg a day is often linked by users to an 18 hour work day, perhaps a double shift of a heavy duty study session.

So how long does modafinil really last?

By all accounts a 200mg dose of modafinil should give you peak performance for at least 8 hours. There should be another 2-4 hours of reduced effects, but still potent enough for the pill to do its job. After that, the medicine is mostly out of your system and its effects will be limited. Bear in mind that individual metabolisms may vary, and the rate of absorption can be affected by eating a large meal before taking a pill, for instance.

Make sure that you plan your modafinil days well in order to get the most out of your dose.

01 Jan

Can you Drink Alcohol on Modafinil?

Many medications recommend not drinking due to the possibility of a bad reaction between the two chemicals. This advice is often ignored by many people who find that it is usually a doctor’s over-cautious suggestion, and that little actual harm will come from doing so. However, every medicine is different and in some instances the warning should be taken very seriously.

The makers of modafinil discourage drinking while on modafinil. However there is no explicit warning that combining the two can be hazardous.

Given modafinil’s status as a popular drug for university students, and university students’ penchant for parties, it shouldn’t surprise anyone that there are quite a few reports of individuals mixing the two substances.

Dangers of drinking alcohol while on modafinil

While modafinil and alcohol do not interact in a negative way, one can amplify the other’s side effects.

For instance, both alcohol and modafinil dehydrate the body faster, meaning that if you do not drink more water (which most drinkers often forget to do) you’ll be in for a rough hangover the next day, as well as the potential risk of dehydration and overheating if you’re dancing or in a hot climate. This is very dangerous and care should be taken to stay hydrated every time you’re drinking, modafinil or no.

Another risk is that you can become drunker than you expected. One possible reason for this is that modafinil reduces appetite, and if you have not eaten before drinking you will feel the effects of alcohol faster. Secondly, modafinil combats the depressant effect of alcohol. You may not feel as sleepy or quite as drunk as you really are, leading you to drink more and assume that everything is fine. When the modafinil wears off, or if you continue drinking, you can suffer disastrous consequences. Users have reported drinking to the point of blacking out, a result of not being aware of how intoxicated they actually were.

Safely drinking alcohol on Modafinil

If you have taken modafinil and you are going to be drinking, you should exercise caution. Eat regularly as you normally do, even if you have a reduced appetite. Make sure to drink more water than you typically would, although this may mean a few extra trips to the bathroom. Above all, do not drink in excess. Respect your regular limits with alcohol, even though modafinil may enable you to surpass them for a moment, the consequences later can be serious.

When it comes to drinking and medication, safety should be your first priority. Avoid mixing modafinil and alcohol, and do not use modafinil as a means to stay up and party all night. If you’ve taken modafinil in the morning or early afternoon and are going out that night, be aware that it takes over 12 hours for modafinil to leave your body. Don’t forget about that dose you had earlier in the day. Be smart with your smart drug.

25 Dec

Modafinil Makes you Smarter by Improving Cognitive Functions

For several years claims have surfaced reporting that modafinil will make you smarter, learn faster, and improve your focus and attention. A stern debate has evolved, with some sides claiming that modafinil makes no difference and that any gains are simply a result of the placebo effect, and others upholding the statement that modafinil will make you smarter, in a sense.

Fortunately this year a major review of several clinical trials has been released. It thoroughly examined 24 studies from the past 12 years, and gathered up all of their findings under one roof. Peer review is an excellent way to make sense of all of these complicated experiments, and at last we can put the topic to rest.

We’re going to look at three areas that are often cited as improved by modafinil: Memory, Executive Function, and Attention.

Modafinil Makes you Smarter: Memory

Memory is complex, but it’s imperative to learning. If you can’t remember what you saw in your last class, then how will you build on that in the next one? Long-term memory on modafinil has not been investigated, but it has been shown to improve short-term memory, which eventually will become a long-term memory if it’s used again.

Multiple studies looked at both verbal and non-verbal short-term memory. Why is the difference important? Verbal information is processed and retained in different parts of the brain, and therefore they can be affected differently by modafinil. Much of your speech processing is localized in the left side of the brain, which modafinil tends to excite. Non-verbal information might be related to remembering a phone number that somebody wrote down for you, while verbal information could be compared to remembering your girlfriend’s birthday after she tells you for the hundredth time.

In both cases modafinil showed an improvement in performance, although there were in some instances slight increases in response time, meaning that it took modafinil users a split-second longer to connect the dots and recall the information. That drawback is negligible compared to the performance gains seen on the tests. While some studies showed no improvement, the majority did and none revealed negative results.

Modafinil Makes you Smarter: Executive Function

“Executive functions mediate the selection and manipulation of incoming information, use of that information to construct and initiate action plans, and enlistment of other cognitive functions and brain regions into complex task-oriented networks (Diamond, 2013).”

The frontal lobe is where most of our executive function takes place. Much as its name implies, executive function is similar to the job of a CEO, and your CEO’s office is the frontal lobe of your brain. The frontal lobe takes data from all of your senses, makes sense of them, and formulates a plan to deal with that situation. In addition the area checks with your memories and imagines possible outcomes for any given scenario. In short, all of your decisions are made here.

Modafinil was found to provide two benefits in this regard: Inhibitory Control, and Fluid Intelligence. Inhibitory control is basically your brain’s way of discarding or ignoring information. If your frontal lobe is working well, it’ll quickly throw away whatever information doesn’t help form a good conclusion. This is great for when you’re studying, because it means that as you read your material you’ll be able to sort through it faster and find what you’re looking for without getting confused by other data.

“Fluid intelligence is the ability to cope with novelty, to think rapidly and flexibly, and to see relations amongst items independent of acquired knowledge, and is predictive of life outcomes such as income, performance at work, and health (Au et al., 2014, Sternberg et al., 2013).”

This right here is the most impressive improvement modafinil made. Studies have consistently shown that one’s fluid intelligence, or in other words your ability to intelligently navigate ever-changing circumstances (that flow, like a fluid), is indicative of your success in life. Life is constantly raining down new problems for us to manage, and having the ability to see through the blurry windscreen and arrive to your destination is essential. Modafinil users exceeded their non-modafinil counterparts in several portions of the test.

Modafinil (doesn’t) make you smarter: Attention

Hold on, could it be that modafinil’s most famous feature, powerful focus and attention, is all a myth? The same study explained attention as the combination of three factors:

  1. Selective attention– the ability to detect specific stimuli within an environment containing distractors
  2. Sustained attention– the maintenance of a consistent behavioural response during continuous or repetitive activity
  3. Divided attention– the ability to allocate cognitive resources to two or more stimulus features or separate tasks

The study found that none of these were consistently improved. In each case a single study or two found positive results, but the overwhelming majority of the 24 in question proved negative.

However another attribute of attention is alertness, which can be considered as your sensitivity to an outside stimulus. In this case, modafinil did improve alertness as subjects were more responsive to stimuli.

Apparently modafinil is not really improving attention so much as it improves the mind’s ability to sort through information (the inhibitory control mentioned above.)

So does modafinil make you smarter?

In a word, yes. It will improve your cognitive functions while on modafinil, as well as enhance your short-term memory. But do not expect permanent gains as these boosts are only temporary when using modafinil. The conclusions of this study reported that more standardized methods are needed to really be able to quantify this data, so hopefully we’ll have more news for you soon.

19 Dec

Modafinil in the News

Modafinil in the News

Modafinil.co.uk periodically brings you the latest news stories regarding modafinil. This time around we have a pair of polarizing articles on modafinil.

Can you be Limitless with Modafinil? (CBS News)

The first of these comes from CBS’s New York affiliate, boldly comparing modafinil to the drug from the hit movie and now television series “Limitless”. CBS’s reporters discussed the pill with several experts who suggested that there is no strict increase in intelligence with modafinil, rather the medicine makes accessing that brain power easier.
Undoubtedly this article is a pseudo-advertisement for CBS’s own aforementioned program, hence the multiple references to the title “Limitless” in the article and an internal link. Still, it provokes one of the important debates regarding modafinil: Does it actually make you smarter? That’s a topic we’ll tackle another time. Regardless, seeing a mainstream media outlet from a major city report on modafinil is indicative of its growing popularity.

Banned from Sport for Modafinil (The Guardian)

The Guardian has brought up modafinil in a less positive light. Two of the UK’s top rowers were drug tested after their performance in an international competition in Belgium. One of the two failed his test for modafinil which is a banned substance in the rowing community.

Why is modafinil banned in many sports circles? This is largely due to the perception that modafinil could increase a person’s stamina or focus beyond the normal levels seen in the sport. Whether or not this is entirely true has yet to be seen as no serious clinical trials have examined modafinil’s direct effects on athletes in the field. However, many major sports leagues have declared the substance taboo with serious penalties for non-compliance.

And it’s not the first high-profile case either. Kelli White, a star female US sprinter, was handed a 2-year ban for modafinil, amongst other substances. Her record breaking runs were wiped out, and her career stagnated shortly after.
Athletes need to be extremely focused mentally, regardless of the sport they’re a part of. Given that competition is so fierce at the national level, it’s no surprise that some athletes seek out an edge over their opponents. Does it work? The few players who’ve been banned for modafinil were on the top of their game at the time.

The Cure for Laziness (Inverse)

This article by Inverse proposes widespread use of pharmaceuticals such as modafinil with an aim at ending chronic laziness. It even goes as far as to point out the glaring contradiction between caffeine’s acceptance and the stigma surrounding “doping”. Why is one okay and the other not? The article brought up a great point: Self-medication is as old as time and has taken many forms. Substances like modafinil are just the latest chapter in a long history book.

Modafinil and its ilk raise several important questions for ethics and humanity’s future. That might seem like hyperbole, but when you stop and consider the rapid advancements in medical science, the present-day realities of bionics, and ongoing research into integration between man and machine, we have to ask ourselves how far we are going to go to make our bodies and brains better. I for one welcome our pharmaceutical overlords.

That’s all for now. Keep checking in for more modafinil news stories and the latest information and updates worldwide.

17 Dec

Provigil in the US Military

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Provigil in the US Military

Provigil?

In the movies, we see superhuman soldiers fighting off alien threats and we are enthralled by the idea of becoming such a person. Well, reality has caught up with the movies. The military has been experimenting with various means to expand the capabilities of their troops, pilots, and sailors to give them an edge over the opposition and the drug Pro vigil is but one of the myriads of ways they are attempting to create the War Fighter of the future.

 

The drug allows you to stay awake and provides you with the ability to focus and perform at a level that is unheard of. Students in schools in the EU, Asian, and here have heard about the drug and are using it in record numbers to enable them to cram for exams and burn the midnight oil.

 

Today, we will exam Provigil and let you look behind the hype and myth and see if the drug can be of use to you in your life.

Modafinilimage38

Today military pilots use it to stay alert flying over dangerous territory and even militants have started using it in foreign nations.

 

Lawyers, 5th Ave Ad gurus, and Wall Street market savants are using it as well. This gives them all almost superhuman concentration and the ability to work for long periods of time without tiring or the need to sleep.

 

To learn more, just keep reading this article.

 

History

The drugs real name is Modafinil and is a schedule IV controlled substance. However, doctors perceive it for a number of conditions on a regular basis for Shift Work Sleep Disorder (SWSD), sleep apnea, narcolepsy. During exams at many university bootleg and knockoff drugs, are peddled to the many that are competing for high grades and class rankings that make them attractive to employers who are seeking only the best of the best for the few high paying positions that they are looking to fill.

 

The drug itself was patented in 1990 the drug has been around for some time now and a French company, Cephalon holds the primary patent. However, many other companies have created generic forms of the drug. In some cases, litigation is continuing by Cephalon against the most aggressive of them.

 

The drug is manufactured worldwide and in the UK is OTC, Germany has made it a prescription drug, and in Mexico, you can buy it OTC. China is one of the leading makers of this and other generic and knockoff drugs of this type and is a major source for the many athletes and bodybuilders who use it to have more stamina and endurance and is the subject of controversy in the world of professional sports. Just in time for the 2004 Summer Olympics, it was banned by WAD who oversees the use of drugs in professional sporting events.

 

Baseball great, Barry Bond blew the lid off the use of drugs in Pro-sports and Modafinil was mentioned in his expose of the practices of his fellow athletes, how widespread the practice is as yet unknown, as most are reluctant to give away the secrets of their athletic prowess.

 

 

 

Benefits of Provigil

Provigil’s many benefits have been showcased and ABC has run a number special reports on the drug, as well as the many who use it, as it is the secret of many high-powered execs’ successes. Lobbyists in Washington use it regularly to get the edge over Joe public as they line up to garner support for their clients who want to feed from the public trough of money that congress apportions every year.

Not only government hacks but professionals in many fields also use Pro vigil to get the edge.

 

Engineers, programmers, and web designers can work 12 hours at a time to produce a prodigious amount of work, websites, and code required by their bosses who look the other way as success brings in the bucks to the tune of millions of dollars every year.

 

Something is happening in the world of work as prescriptions for the drug has increased by almost 75% between 2007 and 2011. This either means that work stress and long hours are the norm or that enterprising individuals know the only way to win is to use this or many of the other Nootropics now available on the market today.

 

Research is sketchy

Drug companies all have glowing reports on their brand of “Super Pill” and mainstream science is leery of saying anything one way or the other. Doctors will only say that long-term sleep deprivation is harmful and 12 weeks is the recommended length of time for taking the drug without a break.

 

Doctors are also at a loss as to how and why the drug works at all. This has not stopped some scientists to recommend removing all restrictions on the use of the drug as we in America are falling behind countries that openly use performance-enhancing drugs. The EU and China are known to be heavy users of Nootropics and it is considered a normal way of achieving success and is done openly and not in secret as here in the US.

 

 

 

The Long-Term vs. Short-Term usage and risks

Under 12 weeks the drug can turn you into a human dynamo and you can work you shift with more energy and focus that you have ever known. However using the drug for over the recommended 12-week limit one runs the risk of buildup of toxins and stress on the heart, kidneys, and liver. Rashes have been noted in some and if this occurs stop taking the drug and seek medical assistance as this may indicate an allergic or more serious reaction to this type of drug.

 

However, with proper management and adherence to the recommendations laid out by your doctor the drug has shown to have very few side effects. It has been in general use since the 1990s and its benign qualities have been noted by the thousands who use it every day. This is especially true as if you follow the recommended dosage of 200mg before your shift or work day.

 

A certain Web developer that runs a billion dollar software empire takes his at about 5 am and he has been known to take long flights to visit other countries, get off the plane, and at speaking engagements generates millions of dollars in revenues during one speaking tour for his company. He openly admits he owes his success to Provigil.

 

 

 

Is Provigil legal?

As mentioned before it is available via prescription and increasingly doctors are more liberal in their policies about prescribing the drug as many of them feel this and other Nootropics should be made OTC and available for use by everyone in America.

 

Final thoughts on Provigil

Today students are using this “Super Drug” as the military have term Pro vigil and they as well as professionals from all walks of life have turned to the is drug that was approved in 1998 by the FDA to treat certain sleep disorders.

 

One the door was opened we normal people have been kept mostly in the dark as those who use it want to have it for themselves so they can blast past us mere mortals and go for the gold in not only the professional arena but in sports and other athletics as well.

 

Today, we have removed the veil, let you see how many are achieving results, not by blood, sweat, and tears as commonly thought and propagated in popular culture. Instead, they owe their successes to a “Super Drug” that you too can get access through via your doctor or through other channels. Take a look at Amazon (Under Nootropics) and you will find many drugs that are similar to Provigil and give you the same results and can take you to success as well.

10 Dec

How does Modafinil work?

In addition to Modafinil, we also sell Analogue’s, such as Adrafinil, Hydrafinil, Fladrafinil, and Flmodafinil, Click this Link to checkout our homepage store

 

Now there’s a question that needs answering, and it’s one that people have been asking for several years now. There’s a bit of a myth that nothing is known about how modafinil affects the human brain, and that it’s mostly a mystery. In fact, there are quite a few studies out there that have examined small groups of patients with fMRI technology while using modafinil, so we DO have information and CAN answer this question to an extent.

Neurotransmitters at play

To set the table for this, we should go back in time just a bit. Modafinil was supposed to be a non-dopamine alternative to the classic amphetamine family of wakefulness drugs. Amphetamines increase the amount of dopamine in the brain. Dopamine is basically the brain’s way of saying “Hey, I like what you did there! Do that again!” Dopamine causes euphoria and reinforces our good actions. It pumps us up when we do something right. Think of the thrill of nailing a play in sports, perfect marks in school, absolutely killing a job interview, you’ll find the same dopamine rush at the end.

Part of the problem is that dopamine active drugs tend to be addictive, and modafinil was presented as the anti-dopamine alternative. Yet some studies have called that into question.

A 2009 JAMA study actually revealed that modafinil increases dopamine in the brain, much like the aforementioned amphetamines. It appears to do this by blocking dopamine transporters. Dopamine, like every other neurotransmitter, is stored in the brain until it is needed, then it is transported out to trigger a certain response, like the ones we just mentioned. If you block the transmission, however, then as your brain continues to produce dopamine as usual you end up with a surplus. That surplus then affects all cells, instead of just specific ones that are targeted by a dopamine release.

The 2009 study tested this by measuring dopamine levels, as well as administering a form of iodinated cocaine which can be detected in an fMRI. It showed that after taking modafinil it was at least twice as difficult for the 11c-cocaine to bind to the usual sites. This is important, because cocaine operates by releasing heaps of dopamine, and it was more difficult for it to work precisely because something was already in cocaine’s parking space: modafinil.

Norepinephrine is another neurotransmitter implicit in modafinil’s mechanism of action. Norepinephrine is in part responsible for a mental state of alertness and attention, and so it seems to be a good explanation of modafinil’s effects. Studies have shown that norepinephrine is slightly increased by modafinil. So modafinil’s mechanism of action can be largely explained by an increase in dopamine and norepinephrine in the human brain, although that’s not the only factor that matters.

Bloody mess

Modafinil increases blood flow in the brain, though not to every place. Both of your pre-frontal cortexes light up like Christmas trees on modafinil. Why does that matter? Your pre-frontal cortex is effectively the part of your brain that handles the most complex thinking and decision making. It’s the part that is most active when you judge whether or not to do something, like when you weigh the pros and cons of an action. It’s also the part of your brain that cares most about reaching goals and planning for the future.

So increased blood flow here means increased activity and that means better brain performance. Sounds like it’s starting to make sense.

Still, it’s not all entirely sunshine and roses. Modafinil actually decreased blood flow to several parts of the left side of your brain. The left side tends to be the analytical and logical side of the brain, with areas that handle maths quite well. The right side is usually the more creative side, handling abstract thought and imagination. So what does that mean for a modafinil user? You might have increased brainpower when you’re deciding how to handle a task and what to take care of next, but if you were planning on knocking out some maths assignments you might find it harder than you had hoped.

So, how modafinil works isn’t really such a mystery at all. It’s building up dopamine in your brain and that explains many of its active effects. The perceived increase in cognitive function can be blamed squarely on increased blood flow to the pre-frontal cortexes and their role in higher thought. The brain is a fascinating place and it just gets more interesting with modafinil. Hopefully more studies will come out revealing more of its functions.