27 Jul

Modafinil Banned from eSports

eSports and Modafinil

eSports events can regularly pack stadiums

eSports events can regularly pack stadiums

eSports, or in more colloquial terms “competitive video gaming”, is a booming industry.  Estimates put it at over $500 million annually. In eSports, live events host gamers from around the world competing at the highest levels for the most popular games.

While it may seem surreal to think of someone as a professional video game player, it’s possible to earn over $100,000 a year this way. The prizes come from advertisers who take advantage of the huge online streaming community, as well as sponsors. While only a few thousand people may attend an actual event, another 10 million may be watching online. But that prize pool is limited to just a handful of players, with only about 60 taking home more than $100k a year.

Modafinil in the world of eSports

Just as we’ve seen in universities and even workplaces, modafinil can be used to get a step ahead of the competition. Video games demand constant attention and focus, especially since most of the competitive games are first-person shooters or sports games in which a tenth of a second can mean a loss. Adderall and Ritalin have been widely used but modafinil has been spotted more recently as studies show that it is safer than taking amphetamine-based pills.

Practice sessions can often go for hours a day. For the full-time competitive gamer, it’s no different than your regular 9-5 job. Again, modafinil can improve your ability to stay focused on these long practice runs.

The eSports league bans Modafinil

Modafinil was banned from athletic events by the World Anti-Doping Agency after several track and field and cycling competitors used it to gain an advantage. The Electronic Sports League, or ESL, decided to adopt the Anti-Doping Agency’s list of banned substances for its events last year, and since then drug tests are administered randomly to participants in ESL sanctioned events. A cheek swab picks up traces of the banned substances.

Is it fair to ban modafinil from eSports?

As this blog has discussed in the past, there are ethical issues with modafinil in different fields. I have argued in the past that taking modafinil for an advantage in the workplace or in schools is perfectly acceptable because you are not harming anyone else or taking anything away from another person.

But sports is a different story. One of the reasons we universally admire athletes is because their natural talent and ability is so far beyond ours that we can only stand in awe, impressed. When LeBron James leaps up and slam dunks a ball, or when Messi blasts a free kick into the corner of the net, we know without a doubt that we could never do that, and it amazes us. Doping detracts from this as the ability gained is not entirely natural.

eSports is similar. Many people dismiss eSports as child’s play but the growing industry shows that it is in fact a serious venture. And its players should be subject to rules. Modafinil and other nootropics would actually give an eSports player a bigger benefit than someone in traditional physical sports.

Using modafinil to practice is not illegal according to the ESL. Drug tests are not given except at events. I think this is an acceptable way to improve your skills. But if you’re going to compete in any events, abide by the laws at hand.

Still, it’s amazing to see just how many places modafinil has crept into. Wherever there’s competition, someone will be seeking an advantage, and it’s clear that modafinil does provide an advantage in eSports.

 

14 Jul

Modafinil Manages Sleep Debt

Use Modafinil to Fix your Sleep Debt

Picture this: You just got home from a real late night out with your friends and it’s 4 AM. You need to be up at 6 to be at work by 7, and there’s no calling off. You’re in a pickle, what do you do?

While you probably should have planned your activities more wisely, these things happen. Whether you’re a college student who studies (or partied) ‘til dawn, a parent whose children didn’t stop crying all night, or just a regular human dealing with life emergencies that come up, we all have nights where we don’t sleep as much as we should.

Even our regular sleep is declining. The CDC in the US reported that over 30% of adults get 6 or less hours of sleep a night, below the recommended 7 hours or more.

The result is that more people are experiencing sleep deficit, also known as sleep debt. And studies have proven that sleeping for 6 hours a night for 10 nights in a row (a deficit of 10-20 hours) has the exact same effects as missing a whole night of sleep.

Using Modafinil to Cope with Sleep Debt

The classic advice has always been the obvious advice: Get more sleep! Naps are proven to work, but of course we can’t all be nodding off in the middle of class or work. If you can’t adjust your schedule to allow for more sleeping time, then modafinil is an excellent short-term solution.

A 1999 study showed that when people had been sleep deprived (missing one night’s sleep or more) modafinil restored their performance to near-baseline levels. Interestingly, these subjects had no problems taking naps while on modafinil. It seems that when your body is truly sleep deprived, modafinil won’t interfere with sleeping. 

And even doctors on night shift found modafinil extremely beneficial. A clinical trial in 2012 tested modafinil on doctors who had to work all night. A 200mg dose was given to them towards the end of their shift, and then the doctors took tests that measured their decision making, working memory, and planning abilities around 8 AM, after modafinil had taken effect.

The results were impressive. Placebo participants scored much lower than the modafinil tested doctors.

Why Sleep Debt Matters

The effects of sleep debt are detrimental to society. Car accidents increase greatly as studies show that driving without sleep is just as bad as drink driving. Companies lose productivity as workers cannot perform at their regular levels. Students’ grades suffer. And in the case of professions like doctors or emergency rescue workers, a lack of sleep could literally mean the loss of someone’s life.

While modafinil is useful for combatting sleep debt, it still is no replacement for actual sleep. While you might be able to get away with a day or two without proper shut-eye, don’t make skipping sleeping your routine.

12 Jul

Modafinil is a Diuretic, What you need to know

Modafinil is a Diuretic, it makes you lose water

For most people modafinil presents no serious side effects, and even minor ones are uncommon. However, there is one effect that occurs in the vast majority of people, so much so that it’s not considered a “side effect” but simply a natural part of taking modafinil.

Losing water on modafinil

Modafinil is a diuretic, a compound that causes your body to shed its water weight. Many stimulants have this effect to varying degrees. Other products are made specifically for this purpose, often called “water pills”. You might see these advertised as a way to lose weight quickly, though that is risky and even dangerous behavior.

Modafinil’s Diuretic Effect

Obviously water tends to leave your body in more or less one way: Urination. When you take modafinil, you’ll find that you need to run to the bathroom more frequently than normal. This is a perfectly normal effect, so don’t worry. But you should take some precautions.

How a diuretic works

Your kidneys act as filters for the liquids passing through your body. Whatever doesn’t get absorbed back into the bloodstream gets sent out as urine. Diuretics prevent the kidneys from absorbing sodium, potassium, and sometimes calcium. These three elements are more commonly known as electrolytes, those minerals that sports drinks like Gatorade love to harp on about.

Think about how salt quickly soaks up water. That same process is going on inside your body. If you can’t absorb the salt attached to the water, you’ll need to pass it out. That’s what’s going on when you take modafinil.

Is modafinil bad for your kidneys?

When Provigil was released, the FDA recommended that patients with kidney issues avoid taking it. Your liver does the majority of the processing for modafinil, with only about 10% of it being absorbed in the kidneys. So modafinil shouldn’t cause any damage to your kidneys if they are healthy.

In the kidneys modafinil is turned into modafinil acid as it comes into contact with the electrolytes and water in your kidneys. In people with renal issues this can cause irritation and pain. It also explains why your urine can smell stronger or have a different color when you take modafinil. Interestingly, some ethnicities don’t process this acid as well as others.

Avoid dehydration when you take modafinil

A diuretic can cause you to pass an extra liter of water per day! In response you should increase your water intake. However water alone may not be enough. Keep in mind that you are also losing those electrolytes. A sports drink can replenish those valuable components almost instantly, and so can eating balanced meals.

Going to the bathroom more frequently is a fairly generous offer when you consider modafinil’s potent effects on cognition and concentration.

10 Jul

Provigil Reviews of Long-Term Use

Modafinilimage38

Provigil Reviews

What Is Provigil?

Provigil is the brand name for modafinil, distributed by the Cephalon company. It is used to treat excessive sleepiness in adults brought on by sleep disorders such as narcolepsy, obstructive sleep apnea (OSA), or shift work disorder (SWD) by altering the neurotransmitters in the brain. One thing to keep in mind is that it treats symptoms but is not a cure for the sleep disorder itself. Therefore, it is important to continue treatments recommended by your doctor. It may be purchased online without a prescription by other names, although this is a not a safe practice.

 

Provigil is a classified as C-IV and controlled by the federal government via the Federal Drug Administration because of its potential for abuse or dependence.

 

What is it used for?

As stated above, Provigil is used for excessive sleepiness, which can lead to poor work quality, bad judgment, lack of ability or desire to participate in activities, among other things. It also improves memory and is a mood enhancer. In fact, it has gained popularity for treatment of Attention Deficit Disorder because of its enabling effect on concentration. It has also been found in test trials to be effective in treating depressive symptoms in patients with bipolar disorder. It has been used to treat fatigue in patients with multiple sclerosis. It can be prescribed to treat both the fatigue and chronic pain of fibromyalgia. Provigil has been helpful in easing symptoms of methamphetamine withdrawal. It is now being used as an experimental drug in treating the lethargy associated with Alzheimer’s disease. It is being tested in the treatment of myotonic dystrophy symptoms. Its use for post-anesthesis grogginess, schizophrenic impairment, spasticity of cerebral palsy, fatigue of Charcot-Marie-Tooth syndrome, symptoms of fatigue in cancer patients, jet lag, and age-related memory decline are also being investigated.

 

Benefits

The obvious benefit of Provigil is to relieve the drowsiness caused by lack of sleep due to sleep disorders. It is also known as a “smart drug”, thus named because it is very effective Provigil Reviewsin increasing one’s cognitive powers and mental energy. It reduces fatigue, improves memory, increases mental energy, and accelerates cognitive connections. The beauty is that all of this is accomplished without addictive potential.

 

Side Effects

Common side effects of Provigil include headache, back pain, nausea, nervousness and anxiety, diarrhea, insomnia, dizziness, stuffy nose, and GI distress. More serious side effects are skin rash, blisters, or peeling, mouth sores, trouble swallowing, fever, shortness of breath, leg swelling, dark urine, jaundice, and swelling of lips, tongue, face, or throat. You should seek medical attention immediately if you have suicidal thoughts, hallucinations, aggressiveness, chest pain, or uneven heartbeats.

 

Long term use

One excellent attribute of Provigil is that it does not create dependency. Other than that, very little is known about long-term use. That should be comforting, but it may be that there is just not enough data to determine any long-term detriment.

 

Use in Silicon Valley

Provigil has been termed “the entrepreneur’s drug of choice” since it keeps one awake and able to concentrate for long periods of time without apparent side effects. Given Silicone Valley’s reputation for the workaholic environment, it has lead many to embrace this drug to keep up the expectation of massive production.

 

Proper Use

Always take Provigil exactly as directed by your medical care provider. It is usually taken in the morning to prevent daytime somnolence and can be taken with or without food.

 

Dangers of Provigil

The main danger is most likely the temptation to take Provigil more often than prescribed. Although seen in a small percent of users, there is the possibility of fever, sore throat, rash, easy bruising and bleeding, sores on mouth or lips, chest pain, or irregular heartbeat. If any of these symptoms occur, contact your doctor immediately.

 

Conclusion

As with any other drug, there may be side effects. These can vary greatly from one individual to another. It is wise to keep in mind the possible serious effects and consult a health care provider immediately if you notice any of them. If you experience any unusual condition, it would be wise to advise your doctor. However, as drugs go, there seem to be many benefits and very few side effects in a vast majority of cases.

07 Jul

Has the Psychoactive Substances Act made Modafinil Illegal?

The Psychoactive Substances Act Threatens Modafinil

Alright, this is the biggest news to hit the modafinil market since Cephalon’s patent ran out and generic pills flooded the market. And it’s a doozy. In the past, modafinil was completely legal to import into the UK up to a 90 days’ supply of the drug. This wasn’t just for modafinil, but rather all POMs (prescription only medications). However, since the passage of the Psychoactive Substances Act (PSA), fear has spread that these imports will be made illegal. As of May 26th the bill is in full effect. Here is the relevant text from the bill.

A person commits an offence if—

(a)the person intentionally imports a substance,

(b)the substance is a psychoactive substance,

(c)the person knows or suspects, or ought to know or suspect, that the substance is a psychoactive substance, and

(d)the person—

(i)intends to consume the psychoactive substance for its psychoactive effects, or

(ii)knows, or is reckless as to whether, the psychoactive substance is likely to be consumed by some other person for its psychoactive effects.

Let’s break this down: (a) restricts the importation of (b) psychoactive substances. Modafinil clearly qualifies. And (i) prohibits this importation with intent to consume. Because, of course, some people just like to store pills in the closet for the inevitable apocalypse.

Modafinil is still legal to import

Breathe a sigh of relief. The same passage of this bill makes a provision for “medical products”. Take a look at the text regarding this:

(1) In these Regulations “medicinal product” means—

(a)any substance or combination of substances presented as having properties of preventing or treating disease in human beings; or

As modafinil is approved in the UK for treating narcolepsy, modafinil qualifies as a medical product.

Okay, so things are looking good. But there’s one more issue to address. The PSA bill still respects the UK’s list of controlled substances, originally formed in 1971.

But modafinil has never been added to this list, making it legal to import for personal use.

Possession may now be illegal

The PSA bill gives the police considerable power to punish possession of psychoactive substances, including fines and a possible 1-year prison sentence for first time offenses. The bill was designed to target “designer drugs” or “legal highs”, in other words psychoactive substances that hadn’t been classified as illegal drugs yet. As a result, possession of anything psychoactive could be considered illegal.

What this means is that modafinil users should be cautious about keeping spare pills on their person when travelling in the UK. An arrest or a police stop for another reason could turn into an ugly ordeal.

Since modafinil is generally effective for the whole day, you probably don’t need to be carrying pills with you wherever you go. Best to play it safe given this new legislation.