23 Jan

Depression Symptoms Improved by Modafinil

Depression, unbeknownst to many, is one of the most common medical conditions in the world. The WHO claims that 350 million people experience depression annually. While there are many pills that try to alleviate depression’s symptoms, they don’t really offer a cure. Many patients stop taking them due to difficult side effects.

Depression symptoms are complex

But news is showing that Modafinil can have a big impact on people with depression. Depression symptoms are complex and many. At the core of depression is a chemical imbalance in the brain that causes multiple symptoms. Most people just think it means that you feel sad. But it often goes beyond that. Depressed people tend not to experience happiness when they naturally should. For many it’s more of a total lack of emotion. This makes them disinterested in regular tasks.

If you’ve ever wondered why a depressed person can’t just “snap out of it” consider what this means. You get depressed, and your performance at work diminishes. That makes you feel like you’re failing. Maybe you lose your job. It spirals out of control. But now there’s some hope.

Modafinil can improve memory function

Since cognitive functions are also depressed, especially memory and concentration, depression will often cause people to forget important assignments or to miss details in a conversation. A new study shows that Modafinil can improve memory function. The study tested 60 patients and found the Modafinil group did better on memory tests.

This is exciting news for those suffering from depression. Modafinil might be the extra boost they need to stay sharp even when everything else feels dull.

One thing that’s important to note though is the type of patient in the study. They had “remitted depression” which is generally when the depression symptoms subside. They are still present, but are less of a bother. The biggest concern for a doctor is to make sure the patient doesn’t relapse into a full blown depression again. Modafinil would be an excellent tool to keep patients in remission from falling back into the hole.

So if you’re depressed, Modafinil may be able to help you, but consult your doctor. If you’re in remission, this could be a great way to give you a boost and keep depression from consuming you again.

11 Jan

Provigil Prices may Change under Trump

Donald Trump speaks on Drug Prices. Credit: AP

Donald Trump speaks on Drug Prices. Credit: AP

2016 left the world with many questions. The UK voted to leave the EU. The United States elected Donald Trump to the presidency. While immigration and peace in the Middle East tend to dominate the conversation, you shouldn’t ignore Trump’s comments about health care. That goes for people outside the United States as well.

The Affordable Care Act (ACA), also known as Obamacare, has not lived up to expectations. Trump campaigned hard against the ACA, and today he held his first press conference since being elected. In this conference he vowed to “repeal and replace” the ACA with something better. And it may have a huge impact on the price of prescription brand-name drugs, like Provigil, around the world.

Provigil Prices are unique in the US

Countries like the UK have a single-payer healthcare system. The single payer is in fact the government. Since the state provides the care and medication, it buys the medicine its citizens need from pharmaceutical companies. State health providers, like the NHS, negotiate to get the lowest price possible for their medicine. This way they can offer it cheap to people like you and me.

In the UK all prescriptions are sold at a flat rate, meaning that the government probably takes a loss on some and profits off of others. Provigil prices in the UK are the same as every other medicine, but Provigil prices are unique in the US. Because the US lacks a single payer to negotiate on behalf of everyone, pharmaceutical companies can charge much higher prices.

The result is that Provigil prices in the US are over $1,000 for a month’s supply. Insurance companies will usually cover a great deal of this, but if you lack insurance you’re out of luck.

How Trump could change Provigil Prices

Trump stated this morning that he would like the government to negotiate with pharmaceutical companies, just like most other countries. This is unprecedented in the US. Pharmaceutical stocks immediately fell 3-5%. Expect Provigil prices to be cheaper in the United States in the years to come if he follows through.

But this affects everyone else on the planet too.

Why do you think the NHS gets a better deal than the US? Part of the reason other countries are able to pay so much less for their medicine is that the US is paying heaps more! Imagine going out to eat with a few friends, and one of them pays for 80% of the check. Your bill just got lighter.

That 80% number might even be low. Some estimates think the US is responsible for 90% of the industry’s profits.

Expect Provigil prices to rise

If Trump starts hurting the profitability of companies in the US, they’ll look to get more out of other countries’ healthcare systems. The NHS, for instance, might be pressured to pay more for medicine. That, in turn, will lead to you paying more for your prescriptions.

Might be a good time to start stocking up if you’re living outside the US.

 

09 Jan

Lawsuit over Provigil and Modafinil Prices Reaches Settlement

The attorney-generals of New York and Ohio won a settlement with Cephalon, Inc. Cephalon is the pharmaceutical company that invented modafinil. If you purchased name-brand Provigil, or generic Provigil, then you may be eligible for a piece of the pie.

So what actually happened? The $35 million dollar deal was cut behind closed doors, and Cephalon never admitted any wrongdoing. It has to do with US antitrust law and how it works. You can read the full statement here.

Cephalon’s not alone in the lawsuit

Cephalon’s not the only company mentioned. Barr Pharmaceuticals is also on the lawsuit. So is Teva Pharmaceuticals. So how are they connected?

Cephalon’s patent to produce modafinil exclusively was going to expire in 2011. To prepare Barr applied early for FDA approval to produce it. Filing the application early gave Barr time to prepare its facilities for production when the patent eventually would expire. They received permission in 2004.

The lawsuit says Teva skirted the rules

Teva Pharmaceuticals acquired Barr in 2008. Now its Teva vs Cephalon. In the same year as Cephalon’s patent expired, Teva made a bold move. Teva purchased Cephalon in 2011. This meant that Teva would be both a licensed producer of generic modafinil, and the name brand Provigil. Teva event went so far as to apply for a license separate from Barr’s and received it in 2014.

The lawsuit says Teva skirted the rules, because they absolutely did.

This is illegal because it disrupts the market. In a natural market, the generic manufacturer would sell their pills as cheap as possible to encourage customers to stop taking the name brand. But since Teva controlled generic production, they could sell it at a price much closer to the regular price of Provigil. Instead of seeing a massive price difference, customers would see a smaller one, and opt for the name brand drug.

People assume the name brand is better. They are, but not by much.

This lawsuit aims to get some of that money back. The generic should have been cheaper. And that should have caused Cephalon to lowers its Provigil prices. Neither of these things happened.

The attorney-generals’ settlement probably is a tiny fraction of what Teva actually made. Over a million Provigil prescriptions are filled out every year, so a simple $5 increase in price pays for this settlement. The actual difference may have been much more, but to avoid disclosing that information, Teva and Co. have decided to settle this lawsuit out of court.

If you’d like to know if you are eligible for any benefits from the settlement, check out the lawsuit’s page.

 

 

05 Jan

Modafinil vs Adrafinil vs Armodafinil vs Hydrafinil

nuv

Modafinil vs Adrafinil vs Armodafinil vs Hydrafinil

This blog post will go over the top 4 “afinil” products currently on the market and will go over what works best in terms of potency, price, simplicity, and for which works the best on a long-term, convenient basis. I chose to write this article because of the confusion surrounding Modafinil, and because of how many other nootropics are often compared to it, including those that are significantly weaker. This article should serve as a guide for any users who are conficted about “afinil” nootropics and analogues.

What is Provigil (Modafinil)?

Provigil, also known as Modafinil, is the premium nootropic drug, and by far the most popular of the “afinil” nootropics. The only thing stronger is likely Armodafinil, though Armodafinil is much harder to get your hands on, whereas for Modafinil/Provigil, it’s actually fairly simple. Modafinil, while a drug used professionally for Narcolepsy, ADHD (off-label), and COPD, Chronic Obstructive Sleep Apnea, it has become extremely popular Modafinil vs Adrafinil vs Hydrafinil vs Armodafinilin recent decades for use as a “Smart Drug,” Nootropic and Cognitive Enhancer, and has even been deemed the “CEO’s drug” by many tech blogs that write about Silicon Valley and Wall Street.

Modafinil’s use as a Smart Drug has become so popular because it is effective and works better than most of the other nootropic products on the market. Other common nootropics are very subtle, and when comparing Modafinil to drugs like

Piracetam- Original nootropic, very subtle, typically gives a slight energy boost.

Aniracetam- Mostly for anxiety relief

Oxiracetam- Deemed the “speedy racetam.” very subtle in effects, headaches occur if choline not consistently supplied.

Alpha GPC Choline-Good for stacking with nootropics, nootropic effects comparable to fish oil (zilch) on its own.

It’s not even a choice! If you need to get real work done or are in a crunch for time when cramming for an exam, taking Piracetam or Choline just isn’t going to get you there, you need something that works, and something that works amazingly! Provigil is a drug you can actually feel, and it’s been given loads of hype for a reason, it works like a charm, and it works very effectively. Modafinil vs Adrafinil may be the only “nootropic” comparison worth making, and even then Modafinil is about 4 times the strength of Adrafinil.

Checkout these links for Research Studies proving the effectiveness of Modafinil:

https://examine.com/supplements/modafinil/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654794/

https://www.ncbi.nlm.nih.gov/pubmed/19300566

http://www.livescience.com/51919-modafil-improves-attention-learning.html

What is Nuvigil (Armodafinil)?

Nuvigil is likely the only Smart Drug stronger than Modafinil right now. Nuvigil was created by Cephalon several years ago, and is a new and improved form of Modafinil. Names also include Waklert, Armodafinil, Nuvigil, and Alertec, I apologize if I’ve left out any. Nuvigil is, in medical literature and on may nootropics forums, such as Longecity and Reddit deemed to be about 30% more effective on a per milligram basis, whether or not this is factually accurate is up for debate. 150 milligrams of Armodafinil is typically equal to 200 milligrams of Armodafinil.

For more information on Armodafinil, checkout these research links

https://www.modup.net/blog/research-armodafinil/

https://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0009105/

https://www.ncbi.nlm.nih.gov/pubmed/19133704

What is Adrafinil (Olmifon)?

Adrafinil is also a erogenic drug that is significantly weaker than Modafinil by a margin of about a third. 100mg of Modafinil is the equivalent of about 300 milligrams of Adrafinil and even then Modafinil is much cleaner than Adrafinil. Adrafinil can have some pretty rough effects on your liver if the drug is taken on a regular basis, and in all honesty this is a drug that should only be taken short-term, if its taken at all. It also is known as Olmifon, and is sold by a number of nootropics websites, including peaknootropics.com, nootropicscity.com, smartdrugsforcollege.com, absorbyourhealth.com, amazon.com, ebay.com, powdercity.com and the like of those that sell nootropics. Compared to Modafinil, it is much harsher and less effective.

Research on Adrafinil:

https://examine.com/supplements/adrafinil/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654794/

What is Hydrafinil (9-Fluorenol)?

Hydrafinil, also known by many companies as Fluorenol, is an interesting analogue of Modafinil. It’s hard to find and only a handful of companies sell it, it’s not really a nootropic and instead is more of an RC nootropic (research chemical) because of how little research their is on the drug. Hydrafinil is supposedly a more euphoric form of Modafinil, but having tried it personally, I can say that its similar but much less energizing, it also only lasts about 3 hours, and gave me a horrible headache after the drug came down. Rare to find, and not very effective, steer clear.

For the limited research available, read on:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654794/

http://mentalhealthdaily.com/2015/12/23/hydrafinil-fluorenol-a-modafinil-analogue-with-questionable-safety/

https://www.modup.net/blog/hydrafinil-launch-ceretropic/

Sources: 

  1. https://clinicaltrials.gov/ct2/show/NCT02886130
  2. https://www.ncbi.nlm.nih.gov/pubmed/1662399
  3. https://www.ncbi.nlm.nih.gov/pubmed/1409797

*Disclaimer: Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Always consult a physician if you are unsure about taking a new supplement. Do not take this supplement if you are under 18, if you are pregnant, nursing, or have any cardiovascular issues. Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement, since there are many unaccounted variables, which fall outside the scope of the studies. All refunds must be brought to our attention within 7 days of delivery in order to be considered for reimbursement

 

03 Jan

Reach your Goals in 2017 with Modafinil

Successfully recovered from your New Year’s festivities? The start of a new year is a great time to get your ducks in a row and make plans. With your hangover gone now’s the time to set your 2017 agenda with some New Year’s Resolutions. Whether you have big goals or small ones, those objectives help you organize your life and accomplish greater things.

Yet, if you’re like most people, you’ve made resolutions at one point or another and then failed to fulfill them. Nobody’s perfect. Don’t let previous failures keep you from glory in 2017! All you need is a little extra commitment. Modafinil can help you reach your goals. Let’s look at some of the most common goals that modafinil can help you with.

#1 2017 Goal: Save Money / Pay off debt

We’d all like to pay off some debt or save up for a big purchase. Maybe it’s a house or a new car. A holiday abroad. Whatever the case is, saving money always sounds easier than it really is. Modafinil can make a difference in two phases of this game.

First off, you need to know your finances. This can be hard for some people. If your income varies from day to day, common for people in the service industry, you need to get into a habit of recording what comes in and what goes out. Salaried workers have it easier. Regardless of your circumstances, take some modafinil and then take charge! Nothing like the focus of modafinil to help you map out your money in an extremely detailed manner.

And when it comes to the actual savings? Modafinil’s cheaper than your daily cup of coffee. If Starbucks is stealing your income, switch it out with modafinil.

Best part? Modafinil will get you to produce more, making it easier to earn more and reach your savings goals.

#2 2017 Goal: Lose weight / Get in shape

Drive up to any gym after January 1st and you’ll see a full parking lot. Come back in February and it’ll be empty. The gym is work. It’s tough. Diet and exercise are two ugly truths we have to face in order to get in shape. If your goal is to drop a few pounds, modafinil could be key to helping you out.

For starters, Modafinil curbs your appetite. Mental Health Daily has a great article on all the ways modafinil can contribute to your weight loss plans. Eating less is a big one. You’ll still feel hungry and need to eat, but you’re more likely to eat less. Starving yourself only shuts down your metabolism. You have to keep eating, but in moderation. Modafinil-eration anyone?

And that energy boost you’ll get helps you work out longer and harder. See better results in less time as you make those workouts count. The added focus helps with form and concentration on your exercises. Great if you lift.

If your goal is to get in shape, modafinil can help you.

#3 2017 Goal: Get an education

Maybe you just finished high school and you’re thinking about entering university. Or perhaps you’re a working adult whose career isn’t moving forward fast enough. In either case, getting an education is one of the best goals you can have. But it can be tough. Universities are increasingly competitive. Students put in long hours preparing for tests and completing assignments. Especially for the working professional who wants to get ahead, the extra load of university work can be daunting.

There’s a reason modafinil is mostly consumed by students: It helps. You’ll get the focus you need to concentrate on your classes. The energy will help you work and study at the same time. And, as studies show, you’ll do it all better.

Make 2017 the year of you. The year of success. With some hard work and some modafinil to make it easier, you’ll find yourself looking back on a great year as you reached your goals. Next year’s champagne will be special.