11 Aug

Modafinil can help to treat Premature Ejaculation (PE)

Our last article talked about women’s reproductive health as it examined the impact modafinil can have on hormonal birth control. Today we switch sides and discuss the possible benefits of modafinil on men. While it might be an awkward subject to talk about, studies have shown tha tmodafinil can be used to treat premature ejaculation, or PE.

The PE problem

Surveys show mixed numbers but often conclude that at least 1 in 5 men is affected by PE, and most researchers guess that the number is higher due to the fact that men tend to underreport their sexual problems. PE in particular can be a very frustrating condition and carries with it serious mental stigmas that can lead to feelings of inadequacy, embarrassment, and even depression.

Modafinil to treat PE

Current PE treatments are typically of two varieties. One involves the use of numbing agents, which cut down on the pleasure a man experiences during sex and, hopefully, increase his performance time. However, this method has the obvious drawback of reduced pleasure and can be uncomfortable to use, requiring the application of topical creams or gels.

The other option is to take anti-depressant pills called SSRIs. This is by far the most effective PE treatment, but naturally presents other side effects and potential mental issues. Antidepressants were not designed for people with normal healthy brains, making this treatment potentially risky for some. In addition, the pills in question tend to be very expensive.

But a study from 2009 on rats, followed up by a 2015 investigation on humans, has shown that modafinil can dramatically increase the duration of sexual activity. In one man that was tested his average time went from less than two minutes to about fifteen, well above the average.

New types of Modafinil for PE

For modafinil to work effectively against PE, the sexual activity needs to occur during the half-life of modafinil. For regular modafinil blends this means within 10-12 hours of dosing. Most people take it in the morning, but then the pill has worn off by the time your dinner date is over. But because modafinil also has the tendency to keep you wide awake, it wouldn’t make sense to take it immediately before having sex. So we’re stuck somewhere in the middle.

A patent was filed a few years ago for various forms of “on-demand” modafinil. This would use a different form of modafinil, the d-modafinil molecule, which only has a half-life of 3-4 hours. It could be delivered in other forms besides a pill, such as an inhaler or chewing gum. The shorter half-life means that you could easily take this modafinil in the evening, have a fun night, and fall asleep shortly after.

So men, keep your eyes peeled for more news on modafinil, and women, maybe buy your man a pack or two and give it a test drive if he’s been leaving you less than satisfied.