16 Jun

Modafinil vs Adderall vs Ritalin vs Focalin vs Dexedrine

Human Nerve Cell Synapse Receptor

Modafinil vs Adderall, and the Benefits, Dosage and Side Effects of Each Drug

The debate of Modafinil vs Adderall is a very common and popular one, and most user reviews online put Modafinil as an equally effective drug in comparison to Adderall, just with less side effects and a longer duration of action. Potent stimulant drugs like Modafinil Modafinil vs Adderalland Adderall are commonly taken by entrepreneurs, college students, and those in high pressure sales or high-risk jobs that require users to be on their A-game as much as possible. For the gold standard in all things nootropics, Modafinil and Adderall are most people’s go to because of just how strong and effective these stimulants are as cognitive enhancers, as well as for how long they last and how much energy they give users. For productivity levels, Modafinil and Adderall are both very powerful Smart Drugs, and through the duration of this blog post, we’ll compare Armodafinil and Modafinil vs Adderall to see exactly what each drug is like among users who take it.

What is Modafinil?

Modafinil is a wakefulness-promoting drug that is commonly used for Narcolepsy, ADHD, Chronic Obstructive Sleep Apnea, and for cognitive enhancement as a Smart Drug. Deemed the “CEO’s drug” by many, Modafinil helps users to increase their mood, memory, focus and energy levels to fairly significant degrees. Modafinil is very frequently compared to Adderall because of how both drugs have strong stimulating and euphoric effects, and of how both typically last a very long time.

Benefits of Modafinil

Modafinil has a host of benefits with regards to its abilities on improving cognitive functioning, including the improvement of memory, mood, focus, energy levels, productivity, mental endurance, and persistence, in those users who take it. But what causes this directly, and what neurotransmitters does Modafinil affect which create these powerful cognitive enhancing effects?

Modafinil affects a set of primary neurotransmitters in the brain that are responsible for pleasure, concentration, motivation and motor skills. The main receptors of these are:

Dopamine-Primary neurotransmitter involved in focus, motivation and pleasure. Released in natural activities like sex and eating, as well as when accomplishing a difficult goal-making money has also been linked to a significant release of dopamine, as has falling in love.

Serotonin-Help to balance out the manic highs of dopamine by relaxing users.

Histamine-Primary wakefulness neurotransmitter.

Norepinephrine-Jump starts the body and gives users a physical energy boost.

There are other, more minor neurotransmitters that Modafinil, Provigil and Armodafinil also have an effect on, however those aformentioned are the main neurotransmitters that create the noticeable and stimulating part of Modafinil’s effect.

Dosage of Modafinil

Typical Dosages of Modafinil range from 100 to 200 milligrams per day and are typically taken in the morning. 100 milligrams is usually the minimum effective dosage of Modafinil, and is the dosage at which effects are most frequently felt, whereas 400 milligrams serves as a type of ceiling dosage of the drug, meaning that it is the point at which side effects outweigh the potential benefits of the drug.

There is also a ton of research present currently on Modafinil, the gist of which can be found right here:





The world’s first true “smart drug” enhances cognition and is deemed safe by health experts



Common Smart Drugs that are Stacked with Modafinil

A myriad of signature Smart Drugs and nootropics are frequently stacked atop Modafinil, and among these include:

Piracetam-The original nootropic Smart Drug, first founded in the early 1960’s by a Russian scientists, since Piracetam’s inception and since the rise of movies like Limitless and Lucy, Piracetam has become a mainstream nootropic and has pushed the use of Smart Drugs more frequently online.

Aniracetam-An enhanced version of Piracetam that is around five times as powerful, it also has a potent anti-anxiety effect to it that Piracetam lacks, use with a choline source for best effects.

Oxiracetam-Called the speedy racetam for its potent energy boosting effects. Used with a choline source this drug can be very effective long-term, generally said to be about fifteen times stronger than Piracetam.

Pramiracetam-Thirty times stronger than Piracetam and known primarily for its potent memory benefits.

Phenylpiracetam-Forty times more poweful than Piracetam and with an added stimulant effect, generally speaking Phenylpiracetam is very euphoric and improves focus much more than Piracetam does.

Noopept-Around 1000 times more potent than Piracetam, and very strong when stacked with other related stimulant nootropics like Modafinil.

And a host of other similar and related nootropics.

How to Use Modafinil Properly, and Which Drug is Safer When Comparing “Modafinil vs Adderall”

When looking at Modafinil vs Adderall with regards to overall safety, Modafinil is usually going to be the much safer drug. It is less addictive and lasts much longer, and is generally considered a “wakefulness-promoting,” drug, vs a stimulant like Adderall. Seeing as if Adderall is also an amphetamine, it is incredibly potent yet also incredibly addictive, it is very easy to get hooked on and most users develop a tolerance to the drug’s effects quite quickly, as is true with nearly all pshycostimulant ADHD medications, including Ritalin, Modafinil vs AdderallDexedrine, Desoxyn, and the like of similarly related stimulant drugs for attention and focus issues. Modafinil is very difficult to get hooked on, does not develop tolerance rapidly at all, and just came out with research claiming that it is in-fact the world’s “first safe Smart Drug.”

Modafinil vs Adderall With Regards to Addiction Risks

As stated in the former, Adderall has way more addiction risks than Modafinil does, seeing as if Adderall is an amphetamine based drug and Modafinil is a eurogenic stimulant and wakefulness-promoting substance, acting on the histamine neurotransmitters rather than the dopamine ones. While it is possible to experience a mild crash or a slight withdrawal from Modafinil when the drug is taken obsessively and in very high amounts, this is very rare and most users never experience this when using the drug.

Modafinil vs Adderall Regarding Potency

While Adderall is actually more potent than Modafinil, and offers a much stronger “kick in the pants,” and euphoric coming up that you can feel, it is short lived due to the advent of tolerance, causing Modafinil to be the stronger drug long-term. If you’re looking to take a stimulant drug to boost productivity, mood and energy levels, Modafinil is the better drug long-term, and over the months and years of use, you’ll get much more out of Modafinil than you will out of Adderall.

Modafinil vs Adderall vs Ritalin vs Dexedrine, and Other ADHD Psychostimulant Medications

Now let’s look at several other stimulant drugs talked about infrequently in this article, those being Ritalin, Dexedrine, Focalin, Desoxyn and Concerta. While Adderall is by far the most common of the ADHD psychostimulant drugs that are currently available on the market, it is not necessiarly the most powerful with regards to a one shot deal, the trophy for this would likely go to Dexedrine. With this in mind, let’s take a look at each of these medications:

Modafinil-My personal favorite ADHD medication and stimulant medication, packs a great punch but with a very small amount of side effects.

Adderall-Extremely strong but also very addictive, builds up a tolerance quickly, and has a lot of side effects.

Ritalin-Less addictive and with less side effects than Adderall, cons are that it only lasts for 4-6 hours at a time.

Concerta-Extended release form of Ritalin, same pro’s and cons overall.

Dexedrine-Dexedrine is essentially Adderall without the levoamphetamine isomer, meaning that it is 100% dextroamphetamine, the potent part of Adderall and other amphetaine based drugs.

Final Thoughts on Modafinil vs Adderall, and The Verdict on Which Nootropic is the Better Choice

Well there you have it, the full rundown on Modafinil vs Adderall and how other related ADHD psychostimulant drugs compare. For more information on this and similar topics, checkout our blog for regular updates, and be sure to checkout the categories for hundreds of articles on Modafinil and Nootropics!


  1. https://clinicaltrials.gov/ct2/show/NCT02886130
  2. https://www.ncbi.nlm.nih.gov/pubmed/1662399
  3. https://www.ncbi.nlm.nih.gov/pubmed/1409797

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